IV Edition (2014)
ORGANIZING COMMITTEE
Head of the Conference: Żaneta Matuszek
Piotr Bogdanowicz
Daniel Borek
Joanna Borowska
Zuzanna Borzymowska
Marta Butrym
Martyna Gajos
Klaudia Jączyńska
Aleksandra Klemba
Kacper Kondrakiewicz
Mateusz Kostecki
Marta Królak
Kacper Łukasiewicz
Anna Malinowska
Paweł Mazurkiewicz
Jan Mąka
Katarzyna Mucha
Sylwia Purchla – Szepioła
Róża Kamila Węglińska
Maciej Winiarski
Emilia Wojda
Maja Wójcik
Piotr Lipowiecki
under supervision of :
*Magdalena Markowska, PhD , Department of Animal Physiology, Faculty of Biology, University of Warsaw; Scientific tutor of Neurobiology Student’s Scientific Club, Warsaw, Poland
*Jan Jabłonka, PhD, Department of Animal Physiology, Faculty of Biology, University of Warsaw
Scientific tutor of Neurobiology Student’s Scientific Club, Warsaw, Poland
*Piotr Borsuk, PhD, Deputy Dean for Studies and Students Affairs of Faculty of Biology
SCIENTIFIC COMMITTEE
Prof. Leonora Bużańska, Head of Stem Cell Bioengineering Laboratory, NeuroRepair Department,
Mossakowski Medical Research Centre, Warsaw, Poland
Artur Czupryn, PhD, Department of Molecular and Cellular Neurobiology, Nencki Institute of Experimental Biology PAS, Warsaw, Poland
Jan Jabłonka, PhD, Department of Animal Physiology ,Faculty of Biology, University of Warsaw, Warsaw, Poland; University of Warsaw; Scientific tutor of Neurobiology Student’s Scientific Club, Warsaw, Poland
Prof. Stefan Kasicki, Laboratory of Limbic System, Department of Neurophysiology, Nencki Institut of Experimental Biology PAS, Warsaw; Head of Marceli Nencki Foundation for Support of Biological Sciences,Poland
Magdalena Markowska, PhD, Department of Animal Physiology, Faculty of Biology, University of Warsaw; Scientific tutor of Neurobiology Student’s Scientific Club, Warsaw, Poland
Ksenia Meyza, PhD, Department of Neurophysiology, Nencki Institute of Experimental Biology PAS, Warsaw, Poland
Prof. Andrzej Twardowski, Head of College of Interfaculty Individual Studies in Mathematics and Natural Science, University of Warsaw, Warsaw, Poland
Prof. Daniel Wójcik, Laboratory of Neuroinformatics, Department of Neurophysiology, Nencki Institute of Experimental Biology PAS, Warsaw, Poland
Prof. Andrzej Wróbel, Laboratory of Visual System, Department of Neurophysiology, Nencki Institute of Experimental Biology PAS, Warsaw, Poland
Prof. Andrzej Wysmołek, Institute of Experimental Physics, Section of Solid State Physics, University of Warsaw, Warsaw
PATRONAGES
HONORARY PATRONAGES
University of Warsaw
Dean of Faculty of Biology, University of Warsaw
College of InterFaculty Individual Studies in Mathematics
and Natural Sciences, University of Warsaw
Faculty of Physics, University of Warsaw
Marceli Nencki Foundation for Supporting Biological Sciences
Copernicus Science Centre
Polish Neuroscience Society
www.charactery.eu
neuropsychologia.org
SPONSORS
University of Warsaw
Faculty of Biology, University of Warsaw
College of InterFaculty Individual Studies in Mathematics
and Natural Sciences, University of Warsaw
Faculty of Physics, University of Warsaw
University of Warsaw Foundation
Eppendorf
Shimpol
Elsevier
MEDIA PATRONAGES
eBiotechnologia.pl
Foundation for the Development of the Education System
Laboratoria.net
magazyntuiteraz.pl
www.psychopraca.net
Polish Copernicus Society of Naturalists
Dlastudenta.pl
GUESTS
Prof. Krzysztof Palczewski
Department of Pharmacology, School of Medicine, Case Western Reserve University,USA
A world leader in vision research, Krzysztof Palczewski, Ph.D. is best known for solving the crystal structure of the visual protein, rhodopsin. This seminal advance is especially notable because rhodopsin is now the model for understanding how this large family called G protein-coupled receptors (GPCRs) respond to various cellular signals, including hormones. Indeed, the wide distribution of GPCRs and their roles in a broad spectrum of physiological functions implicated in various disease states has made them the primary target for new drug discovery. Dr. Palczewski’s latest translational research shows promise for preventing/arresting age-related macular degeneration, the major cause of human blindness. Recipient of several national/international honors and supported by multiple competitive National Institutes of Health awards and industrial grants, including 4 R01s and an R24, Center Grant funded at $10.1M, Dr. Palczewski and his team of 20 postdoctoral fellows and Ph. D. candidates have focused their research on the biochemistry of vision. Their investigations involve the characteristics, discovery and therapeutic manipulation of biological molecules in the retina of the eye needed for phototransduction, namely the translation of light into biochemical signals required for vision. Awarder by Polish President with Knights Cross of Order of Merit-Republic of Poland in 2011 – award to foreigners or Poles abroad for distinguished contributions to international cooperation between Poland and other countries
Prof. Bruce Graham
Computing Science and Mathematics, School of Natural Sciences, University of Stirling, Scotland
Dr Bruce Graham is a Reader in Computing Science and Leader of the Cognitive Computation research group at the University of Stirling, Scotland U.K. He has been a researcher in Computational Neuroscience for 24 years, starting as a postdoc in the Centre for Information Technology Research at the Australian National University (1990-1993), followed by 7 years as a research fellow in the Centre for Cognitive Science and Institute for Adaptive and Neural Computation at the University of Edinburgh. He established his own research group at Stirling in 2000. He has an Honours degree in Mathematics (Flinders University of South Australia, 1981; University Medal), specialising in control theory. His PhD is in Chemical Engineering (University of Queensland, 1988) in which he applied fuzzy logic techniques to the control of chemical plants. He was given a Distinguished Alumni Award for contributions to Computational Neuroscience by Flinders University in 2008. He is coauthor of the book, “Principles of Computational
Modelling in Neuroscience” (CUP, July 2011).
Dr Graham home page
Prof. Leszek Kaczmarek
Laboratory of Neurobiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland
Leszek Kaczmarek, born in 1957, is professor of neurobiology and head of the Laboratory of Neurobiology at the Nencki Institute of Experimental Biology since 1996 (chair of the Division of Biological Sciences. PAS: 2003-2007), He is an elected member of PAS, Academia Europaea (presently member of Physiology & Medicine Section Committee), the European Molecular Biology Organization (member of the Council), and served on the Executive Committee of International Brain Research Organization, IBRO and Council of the International Society for Neurchemistry. He gave over 300 invited talks, including plenary at the Polish, Hungarian, Russian, Serbian, Croatian, Slovenian and African Neuroscience meetings. Among his most important scientific discoveries are the role of c-Myc protein in control of the cell cycle, gene expression in mammalian learning, neuronal apoptosis in the adult brain, the role of matrix metalloproteinases in neuronal plasticity, learning and memory, the essential role of cyclin D2 in adult brain neurogenesis and pivotalinvolvement of the central amygdala in appetitive learning. He published over 200 research papers, cited over 7 000 times (H-index = 49) and received several awards for his research achievements, including the Prize of the Foundation for Polish Science (FNP, 2000).
Dr. Valeria Gazzola
Netherlands Institute for Neuroscience, Amsterdam, Netherlands; Faculty of Medical Sciences, University of Groningen, Netherlands
Valeria Gazzola studied Biology in Parma – Itlay – and started her scientific carrer in Rizzolatti’s lab, where mirror neuron where first recorded, with an experimental master thesis entitled: “The role of the somatosensory cortices during the observation of the tactile stimulation of others” which contributed to a publication in Neuron. She then moved to Groningen – The Netherlands – where she completed PhD (cum laude) with a thesis entitled “Action in the brain: Shared neural circuits for action observation and execution” under the supervision of Christian Keysers at the BCN-NeuroImaging Center. For the next three years Dr. Gazzola worked as a Post Doctoral Fellow at University Medical Center of Groningen where she continued to work on shared circuits, with particular emphasis on the idea they are not a single circuit devoted to action perception but a general mechanisms that covers different domains: actions, emotions and sensations. In particular she grew an interest for the role of the somatosensory cortices within the shared circuit network (Somatosensation in social perception. Keysers C, Kaas JH, Gazzola V.; Nat Rev Neurosci). Valeria Gazzola is currently the assistant professor at the University of Groningen and a senior scientist at the Netherlands Institute for Neuroscience in Amsterdam, where financed by a VENI grant from NOW (451-09-006 MaGW), she supervises a group of two PhD students and a master students to investigate the causal relationship between the areas involved in our understanding of the actions and sensations of others, by using combination of fMRI, EEG and TMS.
Prof. Semir Zeki
University College London, England
Professor S. Zeki was Professor of Neurobiology at University College London and currently holds the Chair of Professor of Neuroesthetics there. He has specialized in studying the organization of the primate visual brain and has shown that it consists of many different visual areas, specialized to process different attributes of the visual scene such as form, colour and motion, in parallel but not simultaneously. While continuing these explorations, he has more recently also been interested in learning how visual inputs arouse affective states and, within the relatively new field of neuroesthetics, has explored the neural mechanisms that allow us to experience beauty.
Prof. Brian Leonard
National University of Ireland Galway, Ireland
Professor Brian Leonard studied Medical Biochemistry and Pharmacology at the University of Birmingham, where he also completed his PhD. Currently, he works at National University of Ireland in Galway. His main area of scientific interest is psychoneuroimmunology of mood disorders. Among topics of his research are animal models of depression, biomarkers of major psychiatric disorders, brain-immune axis and the metabolic syndrome in depression and schizophrenia.
Professor Leonard is an author of over 450 publications related to psychopharmacology. He was an editor-in-chief of Human Psychopharmacology and performed many honourable functions in scientific societies, including the presidency of the British Association of Psychopharmacology and Collegium Internationale Neuropsychopharmacologicum. Working as a lecturer at several European universities, including Maastricht Universty, he gained major exeprience in academic teaching. Under his supervision over 70 postgraduate students have been promoted for MSc and PhD degrees. He is an author of two comprehensive academic coursebooks: Fundamentals of Psychopharmacology and Fundamentals of Psychoneuroimmunology.
Prof. Wiesław Nowiński
Biomedical Imaging Lab, Agency for Science, Technology and Research, Singapur
Wieslaw L. Nowinski, DSc, PhD – scientist, innovator, entrepreneur, pioneer and visionary; creator of “world’s most gorgeous” human brain atlases.
His research includes brain atlases, stroke, deep brain stimulation, brain quantification, neuroinformatics, medical image processing, virtual reality, computer-assisted diagnosis and treatment, and future directions in computer-aided radiology and surgery. He has 539 publications, filed 51 patent applications (32 already granted, 15 in US), and developed with his team 34 brain atlas products used worldwide in neurosurgery, neuroradiology, neurology, brain mapping, and neuroeducation. These atlases have been licensed to 62 companies and institutions. He has started 3 high-tech companies from his lab.
Prof. Nowinski has proposed a number of new concepts, including atlas-assisted processing of medical images (US patent), do-it-yourself neurosurgery (published), helical stereotaxy (US patent), operating room of the future (published), probabilistic functional atlas (US patent), probabilistic stroke atlas (patent pending), and atlas-assisted stroke image processing (US patent).
He has introduced several new concepts to atlas-assisted stereotactic and functional neurosurgery. The electronic brain atlases created by him have been incorporated in more than 1,500 neurosurgical workstations and distributed worldwide by leading companies including Medtronic, BrainLab and Elekta.
Fourteen brain atlases have been distributed by Thieme Publishers, New York-Stuttgart to more than 7,500 clinicians and medical institutions. The iPad version is being introduced to medical schools.
Dr. Nowinski has been conferred with 42 awards and honours including Magna cum Laude (radiological Oscar) from Radiological Society of North America in 2009 and 2004; Magna cum Laude from European Congress of Radiology in 2000; Summa cum Laude in 2014, 2012, 2008 and 1997, and Magna cum Laude in 2009 and 2005 from American Society of Neuroradiology; and Highly commended in 2013 (in medical book category) from British Medical Association. Dr. Nowinski has received Knight’s Cross of Merit from President of Republic of Poland in 2005. He has been named The Outstanding Pole in the world in 2012. He was a finalist of Asian Innovation Award 2010 for stroke organized by The Wall Street Journal and Credit Swiss. He has received Pioneer in Medicine title from USA in 2013. In 2014, Prof. Nowinski has been nominated for the European Inventor Award, Lifetime Achievement category (in top 3 European inventors).
His work has been featured in The Wall Street Journal, on The Discovery Channel, BBC (Tomorrow’s World), and Channel News Asia, among others. He is listed in Who’s Who in the World,Who’s Who is Science and Engineering, Who’s Who in Medicine and Healthcare, and Who’s Who in Asia.
GUESTS LECTURES
*Chemistry of vision and inherited retinal disease
Krzysztof Palczewski
Department of Pharmacology, School of Medicine, Case Western Reserve University, USA
Retinal photoreceptor cells can respond to light throughout our lives because they continuously regenerate a light-sensitive chromophore and certain essential structures. Defects in many proteins involved in these processes cause photoreceptor degeneration. Our long-term goal is to elucidate the molecular mechanisms of phototransduction and retinal degeneration to discover therapeutics for inherited human blinding diseases caused by mutations in phototransduction genes.Mutations in the gene encoding opsin, the protein moiety of the light receptor rhodopsin, are among the main causes of these diseases. The interface between the retina and RPE is also especially important because it is part of the visual cycle that can change in response to external stress, genetic manipulations and therapeutics in live animals. To maintain vertebrate vision, the spent all-trans-retinal chromophore released from rhodopsin in photoreceptor cell outer segments must be converted back to 11-cis-retinal, a process largely accomplished in an adjacent layer of the retina called the retinal pigmented epithelium (RPE). The key enzymes involved in this process are ABCA4 transporter, retinoid isomerase (RPE65), esterifying enzyme call LRAT and retinol dehydrogenases. In addition, a number of retinol-binding proteins are involved in this process. Structural studies significantly increased our understanding of the retinoid cycle. Pharmacology combined with structural biology of these enzymes holds great promise for developing innovative therapies targeting retinal diseases.
*Cleavage that links brain and mind
Leszek Kaczmarek
Laboratory of Neurobiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland
The Merriam-Webster Dictionary derives term “Mind” from Old English gemynd; akin to Old High German gimunt meaning memory. Over the last quarter of century we have followed molecular roots of the memory in a hope to identify also building blocks of the mind. Initially, we have identified increased c-fos mRNA levels in memory formation, thus discovering phenomenon of gene expression in learning. Following c-Fos protein function as transciptional regulator, we have focused on its gene targets: TIMP-1 and MMP-9 (tissue inhibitor of matrix metalloproteinases-1 and matrix metalloproteinase-9), composing extracellular proteolytic system that we and others have implicated as a major player in the synaptic plasticity, learning and memory. MMP-9 has been shown first to be activated in dendritic remodeling, accompanying epileptogenesis. Then, functional studies demonstrated MMP-9 role in learning and memory as well as their cellular models and finally epileptogenesis. At the subcellular level, MMP-9 localization and activity helps to explain this role, as the enzyme, its protein and mRNA are all available at the or near excitatory synapses located at the dendritic spines to allow for a rapid, local unleash of the enzymatic activity in response to synaptic stimulation. Furthermore, MMP-9 was shown to directly affect the dendritic spine morphology and excitatory neurotransmitter receptor function and trafficking. In aggregate, the pivotal role of MMP-9 in the synaptic plasticity underlying brain physiology has been firmly established. The present research challenge is to explain possible contribution of the enzyme to such human neuropsychiatric conditions as epilepsy, drug addiction, schizophrenia and autism spectrum disorders to name just those for which such a link has been demonstrated. By these virtues, MMP-9 emerges indeed as a molecular link to the brain molecular underpinning of the mind.
*Modelling the Dynamics of Information Storage and Recall in Neural Circuits
Bruce Graham
Cognitive Computation Research Group, Computing Science and Mathematics, School of Natural Sciences, University of Stirling, Scotland
A subfield of Neuroiformatics, Computational Neuroscience uses mathematical modelling, analysis and computer simulation to study form and function in the nervous system. Modelling has become a vital tool in cellular biological research, particularly for the endeavour of trying to understand the operation of networks of neurons. Mathematical models are used to untangle the myriad intracellular signalling pathways, particularly those underlying plasticity, the electrical properties of neurons and how neural networks may learn and process information. In this talk I will describe models aimed at deconstructing information processing in cortical neural networks, focusing specifically on the hippocampus, a brain area which is vital to the formation of declarative and episodic memories. Cortical circuitry consists of a large population of excitatory neurons, typically pyramidal cells, which are contacted by smaller numbers of heterogeneous populations of inhibitory interneurons. Assuming the excitatory pyramidal cells (PCs) are the “information processors”, then the largely inhibitory microcircuit surrounding each PC forms a control system to modulate information throughput, involving PC spiking activity and synaptic plasticity. To explore this concept we have built a computational model based on the circuitry of the CA1 area of the mammalian hippocampus. With this model we demonstrate possible roles for four classes on inhibitory interneurons (IN) in controlling the storage and recall of patterns of information coded as PC spiking activity. The model is based on published experimental data showing that the PC and different IN populations show phasic activity profiles during the 5 Hz theta rhythm that is prominent in CA1 in rats that are actively exploring an environment. The phasic relationships between cell types can result in PC activity representing recalled information during one half of a theta cycle, while new information is stored by synaptic plasticity of excitatory inputs onto PCs during the opposite half cycle.
*Neuroinflammation and mood disorders: cause or co-incidence?
Brian E. Leonard
National University of Ireland, Galway
Inflammation is an important protective mechanism against invading microorganisms and oncogenes. It is also a component of the stress response. However, whereas inflammation may start as a time and site specific defence mechanism aimed at protecting the body against pathogens, it is also an important mechanism for removing damaged cellular debris by activating the peripheral ( macrophages and monocytes) and central ( microglia) scavenger cells. Should the inflammatory process be prolonged as a result of a chronic infection, autoimmune reaction or chronic stress for example, then maladaptive changes may occur. These changes are associated with a sustained increase in pro-inflammatory cytokines and chemokines and can contribute to both physical ( for example, heart disease, diabetes and cancer) and major psychiatric disorders such as major depression and schizophrenia. Thus chronic low grade inflammation is a characteristic feature of many major psychiatric disorders and now forms the theoretical basis of psychoneuroimmunology. The conceptual importance of psychoneuroimmunology lies in emphasising the holistic link between malfunctioning immune, endocrine and neurotransmitter systems and psychopathology and raises questions regarding the potential importance of a novel class of psychotropic drugs which modulate the immune and endocrine axes.
*Shared circuits, perception and empathy
Valeria Gazzola
Netherlands Institute for Neuroscience, Amsterdam, Netherlands; Faculty of Medical Sciences, University of Groningen, Netherland
Humans are social animals. While it is of cardinal importance for us to understand what other people do and feel, we still lack an understanding of how our brain achieves this function. Research on social perception has focused so far on cognitive processes. I investigate an alternative account: ‘shared circuits’. Shared circuits are brain areas involved when we ourselves do an action, feel an emotion or sense a sensation AND when we observe someone else perform the same actions, express the same emotions and experience the same sensations. Such shared circuits reflect an automatic transformation of what other people do and feel into the neural representation of our own actions, emotions and sensations. Using fMRI we investigate the role of brain regions involved in the execution of actions during the perception of the actions of others; the role of the somatosensory cortices during the perception of other people being touched; and the role of emotional structures (e.g. amygdala and insula) during the observation of the emotional stimuli. The emphasis of the work is to investigate the idea that a single mechanism – shared circuits – could give valuable insights into how we perceive the actions, sensations and emotions of others.
*Subjective truths – from colour to beauty
Semir Zeki
University College London
In his book on Vision and Colours, the German philosopher Arthur Schopenhauer wrote that, “A better understanding and a firmer conviction of the wholly subjective nature of colour is a very good introduction to the Kantian doctrine of the likewise subjective and intellectual forms of all knowledge”. The study of colour vision thus opens an enquiry into the more general question of knowledge, of how we acquire it and how certain we are of what we know. In this lecture, I will start by describing how the brain has developed specialized systems for processing different attributes of the visual world, among them colour, and show that damage to specific parts of the visual brain can lead to specific loss of perceptive abilities, be they in colour, or form or motion. I will also show, by focusing on beauty and comparing it to our perception of colour, that the only truths that we can be sure of are subjective truths; the neural activity mediating these subjective states can now be identified and quantified and raise important issues about what truths these subjective states are pointers to and what, in more general terms, subjective experiences tell us about our brains and the world in which it has developed.
*The human brain and its disorders illustrated by brain atlases
Prof. Wieslaw L. Nowinski
Biomedical Imaging Lab, Agency for Science, Technology and Research, Singapur
This talk has two parts: the first part addressing brain (along with some head and neck) anatomy and the second part about neurologic disorders, both illustrated by brain atlases [1-2].
Brain anatomy covers the cerebrum (with the cortex parcellated into lobes, gyriand sulci), cerebellum, brainstem, spinal cord, (cerebral, posterior fossa and deep) white matter, deep gray nuclei, ventricles, intracranial arteries, intracranial veins, dural sinuses, white matter tracts, visual system, cranial nerves with nuclei, as well as some head and neck anatomy including extracranial arteries, extracranial veins, head muscles, glands, cervical vertebrae, skull, and skin.The presentation will be illustrated by a three-dimensional (3D) and interactive atlas of brain anatomy [1].The anatomic atlas has been constructed from in vivo imaging by employing multiple MR 3 and 7 Tesla, and high resolution CT scans of the same brain specimen. The virtual model of the brain, head and neck has been parcellated into about 3,000 3D components [3-7].
Understanding brain pathology along with underlying neuroanatomy and the resulting neurological deficits is central in medical education and clinical practice. To facilitate and expedite this understanding, we have created a 3D interactive atlas of neurologic disorders to provide the correspondence between a brain lesion and the resulting disorder(s) [2]. Thisatlas, bridging neuroanatomy, neuroradiology and neurology, provides disorder-localization relationships along with neuroanatomy exploration. It presents focal and distributed brain lesions of cerebrovascular [8], cranial nerve-related [9], and regional anatomy-related [10] disorders. These 3D synthesized lesions are labeled with the resulting disorders and associated signs, symptoms and/or syndromes along with the surrounding neuroanatomy.
References
- Nowinski WL, Chua BC. The Human Brain in 1969 Pieces: Structure, Vasculature, Tracts, Cranial Nerves, Systems, Head Muscles, and Glands (version 2.0). Thieme, New York, 2014.
- Nowinski WL, Chua BC, Wut Yi SH. 3D Atlas of Neurologic Disorders. Thieme, New York, 2014.
- Nowinski WL, Chua BC, Qian GY, et al. The human brain in 1700 pieces: design and development of a three-dimensional, interactive and reference atlas. J. Neurosci. Methods 2012;15;204(1):44-60.
- Nowinski WL, Chua BC, Puspitasari F, et al. Three-dimensional reference and stereotactic atlas of human cerebrovasculature from 7 Tesla. NeuroImage 2011;55(3):986-98.
- Nowinski WL, Chua BC, Yang GL, et al. Three-dimensional interactive human brain atlas of white matter tracts. Neuroinformatics 2012;10(1):33-55.
- Nowinski WL, Johnson A, Chua BC, et al. Three-dimensional interactive and stereotactic atlas of cranial nerves and nuclei correlated with surface neuroanatomy, vasculature and magnetic resonance imaging. J. Neurosci. Methods 2012;206(2):205-216.
- Nowinski WL, Chua BC, Johnson A, et al. Three-dimensional interactive and stereotactic atlas of head muscles and glands correlated with cranial nerves and surface and sectional neuroanatomy. J. Neurosci. Methods 2013;215(1):12-18.
- Nowinski WL, Chua BC. Stroke Atlas: a 3D interactive tool correlating cerebrovascular pathology with underlying neuroanatomy and resulting neurological deficits.The Neuroradiology Journal2013;26(1):56-65.
- Nowinski WL, Chua BC. Three-dimensional interactive atlas of cranial nerve-related disorders. The Neuroradiology Journal 2013;26(3):263-75.
- Nowinski WL, Chua BC. Bridging neuroanatomy, neuroradiology and neurology: three-dimensional interactive atlas of neurolgical disorders. The Neuroradiology Journal 2013;26(3):252-62.
PROGRAM
November 14, 2014 (Friday)</strong>
16.00 Registration opens
18.00 Opening ceremony
Opening lecture
18.15–19.15
Chemistry of vision and inherited retinal disease
Prof. Krzysztof Palczewski; Department of Pharmacology, School of Medicine, Case Western Reserve University, USA
November 15, 2014 (Saturday)
09.00–11.20 I SESSION (Neurobiology)
09.00–10.00
Cleavage that links brain and mind
Prof. Leszek Kaczmarek; Laboratory of Neurobiology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland,
10.05–11.25 I seminar session
SI.B1 The science behind homosexuality -a general overview
Dominika Korol
SI.E1 Salivary catecholamines in psychology – MHPG as a marker of central noradrenergic activity
Konrad Rudnicki
SI.B2 Dopamine, plasticity and working memory
Anna Tokarska
SI.E2 Acute restraint stress enhances glutamatergic and attenuates gabaergic transmission in the paraventricular nucleus of the rat hypothalamus
Magdalena Kusek, Krzysztof Tokarski, Grzegorz Hess
SI.B3 Diverse patterns of behavioral deficits in subjects being genetic mouse model of Fragile X syndrome
Alicja Puścian, Ksenia Meyza, Szymon Łęski, Maciej Winiarski, Ewelina Knapska
SI.E3 Anti–interleukin–1beta antibody prevents the occurrence of restraint stress–induced effects in the frontal cortex
Joanna Sowa, Bartosz Bobula, Grzegorz Hess
11.25–11.40 Coffee break
11.40–12.40 POSTER SESSION I (Main Hall)
12.40–15.00 II SESSION (Neuroinformatics)
12.40–13.40
Modelling the dynamics of information storage and recall in neural circuits
Prof. Bruce Graham; Cognitive Computation Research Group, Computing Science and Mathematics, School of Natural Sciences, University of Stirling, Scotland
13.45–14.45 II seminar session
SII.B1 Modeling of seizure transitions with ion concentration dynamics
Damiano Gentiletti, Piotr Suffczynski
SII.E1 Time evolution of SSVEP for different stimulation frequencies
Maria Nowicka, Maciej Łabęcki, Anna Chabuda, Piotr Suffczyński
SII.B2 Analysis of mice behaviour in Python (programming language)
Jakub Kowalski, Alicja Puścian, Szymon Łęski
SI.E2 Spatial properties of steady state visual evoked potentials (SSVEP)
Dominik Krzemiński, Maciej Łabęcki, Piotr Suffczyński
SII.B3 SSVEP generation – simple superposition or internal neural oscillator?
Paulina Anna Dąbrowska, Rafał Kuś
SII.E3 Spontaneous and forced synchronization in Kuramoto model
Aleksiej Khrabrov
14.45–16.30 Lunch break / POSTER SESSION II
16.30–18.50III SESSION (Clinical Neuroscience)
16.30–17.30
Neuroinflammation and mood disorders; cause or coincidence
Prof. Brian Leonard; National University of Ireland Galway, Ireland
17.35–18.55 III seminar session
SIII.B1 Neuropsychology of sleep and dreaming in borderline personality disorder
Monika Słodka, Dagna Skrzypińska
SIII.E1 Neuroradiological changes in the model of experimental acute hydrocephalus in rabbits
Konstantin Senkevich, Olga I. Smirnova, Maxim A. Shevtsov
SIII.B2 Neural Integration in Bipolar Disorder
Wojciech Sak
SIII.E2 Inflammation-driven neurodegeneration: can we stop this phenomenon with cell-based therapy?
Bogna Badyra, Olga Milczarek, Marcin Majka
SIII.B3 Deep Brain Stimulation – history, current and future clinical application
Kamil Polok
SIII.E3 Does systemic inflammation induced in young rats change the seizure susceptibility in adulthood?
Emilia Kosonowska, Zuzanna Setkowicz
SIII.B4 Comparative analysis of the progression of AD among patients with DM type 2
taking and not taking metformin
Piotr Alster
20/21 – INTEGRATION MEETING, Cafe Niespodzianka (Marszałkowska St. 7)
November 16, 2013 (Sunday)
09.00–11.25IV SESSION (Cognitive Neuroscience)
09.00 - 10.00
Shared circuits, perception and empathy
Valeria Gazzola, PhD; Netherlands Institute for Neuroscience, Amsterdam, Netherlands; Faculty of Medical Sciences, University of Groningen, Netherland
10.05–11.25 IV seminar session
SIV.B1 Impact of augmented reality training on cognitive functioning in schizophrenia
Łukasz Okruszek, Anna Schudy, Michał Jarkiewicz, Mateusz Kruszyński, Magdalena Linke, Marek Jarema, Emilia Łojek, Adam Wichniak
SIV.E1 Frontal alpha asymmetry as a leading factor in explaining cognitive changes in depression
Aleksandra Kołodziej
SIV.B2 The influence of working memory capacity on the speed and accuracy of insight
Marta Ratomska
SIV.E2 Nencki Affective Word List (NAWL) in neuroscientific research of emotional dimensions and basic emotions
Monika Riegel, Małgorzata Wierzba, Marek Wypych, Łukasz Żurawski, Katarzyna Jednoróg, Anna Grabowska, Artur Marchewka
SIV.B3 What can event-related brain potentials tell us about semantic processing during language comprehension?
Katarzyna Jankowiak
SIV.E3 The metabolic foundation of intrinsic brain activity
Katarzyna Bienkowska, Valentin Riedl, Urlich Pilatus
SIV.B4 The reader's brain
Joanna Sowa
SIV.E4 Eye fixation-related potential (EFRP) studies: results, applications and challenges
Agnieszka Fudali-Czyż
11.25–11.50 Coffee break
11.50–13.55 V SESSION (Borderlines of neuroscience)
11.50 – 12.50
Subjective truths – from colour to beauty
Prof. Semir Zeki; University College London
12.55–13.55 V seminar session
SV.B1 Dream-reading machine: from imagery to reality
Dagna Skrzypińska, Monika Słodka
SV.B2 Brain perspective on willpower: is self-control finite or unlimited?
Wojciech Zajkowski
SV.B3 Language under a microscope. Is experimental approach useful to development of language evolution as a field of research?
Iwona Nowakowska
13.55–14.00 Short break
Closing lecture
14.00–15.00
The human brain and its disorders illustrated by brain atlases
Prof. Wieslaw Nowinski; Biomedical Imaging Lab, Agency for Science, Technology and Research, Singapore
15.05 Closing Remarks
(with awards for the best oral and poster presentations)
Abstract book (in pdf): AoN4-web (w folderze pliki)
Photogallery: https://www.facebook.com/media/set/?set=a.364710933697407.1073741831.166977096804126&type=3&hc_location=ufi
Promotional movie: https://www.youtube.com/watch?v=jQMzUHgf2ck
Additional materials:
- Interviews: https://www.youtube.com/playlist?list=PLgERAxiahPu_tOQNkDPslpsxcJqbMC4fN
- Guests Lectures: https://www.youtube.com/playlist?list=PLgERAxiahPu-Rmzk-zMOnsU6Exz6VFCTl